I think tighter timings would help especially at lower frequencies, but as Dumo has stated tighter is not always faster.
I could not get 3100 with those timings to pass, but the good thing about my kit is it seems to like voltage, 1.9 on air is fine so I am hoping they do well on cold.
Hiwa is correct being single sided hurts the most, but I think if you could get 4 dimms (full bank) to run it would cancel out the single sided performance hit, but I am sure the IMC would have a tough time coping with full bank, decently high mhz and tight timings (can't believe I just said tight timings and MFR in the same sentence:p).
Thinking about strapping the pot on these suckers but so much more PSC to bin atm.